Meanwell, N. A.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

Don't use scam websites

1

The expanding role of prodrugs in contemporary drug design and development

Rautio, Jarkko, Meanwell, Nicholas A., Di, Li, Hageman, Michael J.

Journal:

Nature Reviews Drug Discovery

Year:

2018

Language:

english

File:

PDF, 1.58 MB

english, 2018

2

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

Meanwell, Nicholas A.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 8.08 MB

english, 2011

3

Old Paths and New Directions: Studying Emotions in the Workplace

Emily Meanwell, Joseph D. Wolfe, Tim Hallett

Journal:

Sociology Compass

Year:

2008

Language:

english

File:

PDF, 141 KB

english, 2008

4

Metallurgical ceramics from Mayapán, Yucatán, Mexico

Meanwell, Jennifer L., Paris, Elizabeth H., Cruz Alvarado, Wilberth, Peraza Lope, Carlos

Journal:

Journal of Archaeological Science

Year:

2013

Language:

english

File:

PDF, 6.14 MB

english, 2013

5

The Experiences of College Students on the Autism Spectrum: A Comparison to Their Neurotypical Peers

McLeod, Jane D., Meanwell, Emily, Hawbaker, Amelia

Journal:

Journal of Autism and Developmental Disorders

Year:

2019

Language:

english

File:

PDF, 697 KB

english, 2019

6

Discovery and Optimization of Novel Pyrazolopyrimidines as Potent and Orally Bioavailable Allosteric HIV-1 Integrase Inhibitors

Li, Guo, Meanwell, Nicholas A., Krystal, Mark R., Langley, David R., Naidu, B. Narasimhulu, Sivaprakasam, Prasanna, Lewis, Hal, Kish, Kevin, Khan, Javed A., Ng, Alicia, Trainor, George L., Cianci, Chr

Journal:

Journal of Medicinal Chemistry

Year:

2020

Language:

english

File:

PDF, 3.60 MB

english, 2020

7

Experiencing Homelessness: A Review of Recent Literature

Journal:

Sociology Compass

Year:

2012

Language:

english

File:

PDF, 99 KB

english, 2012

8

Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design

Meanwell, Nicholas A.

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 6.11 MB

english, 2018

9

Some recent advances in the bacteriology of pasteurized milk

E. B. Anderson, L. J. Meanwell

Journal:

Journal of the Science of Food and Agriculture

Year:

1950

Language:

english

File:

PDF, 544 KB

english, 1950

10

Inhibitors of HIV-1 attachment. Part 2: An initial survey of indole substitution patterns

Nicholas A. Meanwell, Owen B. Wallace, Haiquan Fang, Henry Wang, Milind Deshpande, Tao Wang, Zhiwei Yin, Zhongxing Zhang, Bradley C. Pearce, Jennifer James, Kap-Sun Yeung, Zhilei Qiu, J.J. Kim Wright,

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 205 KB

english, 2009

11

A General Method for the Preparation of 4- and 6-Azaindoles

Zhang, Zhongxing, Yang, Zhong, Meanwell, Nicholas A., Kadow, John F., Wang, Tao

Journal:

Journal of Organic Chemistry

Year:

2002

Language:

english

File:

PDF, 41 KB

english, 2002

12

3-[(5-Chloro-2-hydroxyphenyl)methyl]-5-[4-(trifluoromethyl)phenyl ]-1,3,4-oxadiazol-2(3 H )-one, BMS-191011: Opener of Large-Conductance Ca 2+ -Activated Potassium (Maxi-K) Channels, Identification, Solubility, and SAR

Romine, Jeffrey L., Martin, Scott W., Meanwell, Nicholas A., Gribkoff, Valentin K., Boissard, Christopher G., Dworetzky, Steven I., Natale, Joanne, Moon, Sandra, Ortiz, Astrid, Yeleswaram, Swamy, Pajo

Journal:

Journal of Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 265 KB

english, 2007

13

Synthesis and Structure−Activity Relationships of 3-Aryloxindoles: A New Class of Calcium-Dependent, Large Conductance Potassium (Maxi-K) Channel Openers with Neuroprotective Properties

Hewawasam, Piyasena, Erway, Matthew, Moon, Sandra L., Knipe, Jay, Weiner, Harvey, Boissard, Christopher G., Post-Munson, Debra J., Gao, Qi, Huang, Stella, Gribkoff, Valentin K., Meanwell, Nicholas A.

Journal:

Journal of Medicinal Chemistry

Year:

2002

Language:

english

File:

PDF, 227 KB

english, 2002

14

(Pentamethylcyclopentadienyl)rhodium and -iridium complexes. 37. Synthesis and x-ray structure determination of bis(.mu.3-methylidyne)tris[(.eta.5-pentamethylcyclopentadienyl)rhodium]

Vazquez de Miguel, Amelio, Isobe, Kiyoshi, Bailey, Pamela M., Meanwell, Neil J., Maitlis, Peter M.

Journal:

Organometallics

Year:

1982

Language:

english

File:

PDF, 528 KB

english, 1982

15

Preparation and reactions of sulfonimidoyl fluorides

Johnson, Carl R., Bis, Kostaki G., Cantillo, Jose H., Meanwell, Nicholas A., Reinhard, Michael F. D., Zeller, James R., Vonk, Glenn P.

Journal:

Journal of Organic Chemistry

Year:

1983

Language:

english

File:

PDF, 405 KB

english, 1983

16

Targeting a binding pocket within the trimer-of-hairpins: Small-molecule inhibition of viral fusion

Cianci, C., Langley, D. R., Dischino, D. D., Sun, Y., Yu, K.-L., Stanley, A., Roach, J., Li, Z., Dalterio, R., Colonno, R., Meanwell, N. A., Krystal, M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2004

Language:

english

File:

PDF, 528 KB

english, 2004

17

Human Emotions: A Sociological Theory

Journal:

Contemporary Sociology: A Journal of Reviews

Year:

2009

Language:

english

File:

PDF, 52 KB

english, 2009

18

Technical Requirements and Technical Choices in Pottery Production: A View from the Middle Balsas Region of Guerrero, Mexico

Meanwell, Jennifer L.

Journal:

American Antiquity

Year:

2015

Language:

english

File:

PDF, 9.96 MB

english, 2015

19

Synthesis of 3-Hydroxypyrimidine-2,4-diones. Addition of Anilines to Benzyloxy Isocyanate Synthons to Give N -Hydroxyureas

Romine, Jeffrey L., Martin, Scott W., Meanwell, Nicholas A., Epperson, James R.

Journal:

Year:

1994

File:

PDF, 401 KB

1994

20

Accountability as an Inhabited Institution: Contested Meanings and the Symbolic Politics of Reform

Hallett, Tim, Meanwell, Emily

Journal:

Symbolic Interaction

Year:

2016

Language:

english

File:

PDF, 167 KB

english, 2016

21

Validity of the Elite HRV Smart Phone Application for Examining Heart Rate Variability in a Field Based Setting

Perrotta, A.S., Jeklin, A., Hives, B.A., Meanwell, L.E., Warburton, D.E.R.

Journal:

The Journal of Strength and Conditioning Research

Year:

2017

Language:

english

File:

PDF, 569 KB

english, 2017

22

A general, rotating, hard sphere model applied to the transport properties of a low density gas

Meanwell, Michael, Thachuk, Mark

Journal:

The Journal of Chemical Physics

Year:

2017

Language:

english

File:

PDF, 510 KB

english, 2017

23

Allosteric Modulators of Drug Targets Special Issue

Haskell-Luevano, Carrie, Georg, Gunda I., Wang, Shaomeng, Meanwell, Nicholas

Journal:

Journal of Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 253 KB

english, 2018

24

Direct heterobenzylic fluorination, difluorination and trifluoromethylthiolation with dibenzenesulfonamide derivatives

Meanwell, Michael, Adluri, Bharani Shashank, Yuan, Zheliang, Newton, Josiah, Prevost, Philippe, Nodwell, Matthew B., Friesen, Chadron M., Schaffer, Paul, Martin, Rainer E., Britton, Robert

Journal:

Chemical Science

Year:

2018

Language:

english

File:

PDF, 811 KB

english, 2018

25

TailorâMade Amino Acids and Fluorinated Motifs as Prominent Traits in the Modern Pharmaceuticals

Mei, Haibo, Han, Jianlin, White, Sarah, Graham, Daniel J., Izawa, Kunisuke, Sato, Tatsunori, Fustero, Santos, Meanwell, Nicholas A., Soloshonok, Vadim Anatolievich

Journal:

Chemistry (Weinheim an der Bergstrasse, Germany)

Year:

2020

File:

PDF, 6.60 MB

2020

26

Synthesis of 3H-labeled 2-hydroxy-N-[(1,3,3-trimethyl-[4,5,6-3H]cyclohexyl)methyl]-5-azidobenzamide, a photoaffinity analog of an influenza fusion inhibitor

Douglas D. Dischino, Christopher Cianci, Mark Krystal, Nicholas A. Meanwell, Hiromi Morimoto, Bradley C. Pearce, Philip Williams, Kuo-Long Yu

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1999

File:

PDF, 306 KB

1999

27

Stereoselective reduction via lithium borotritide: synthesis of 3H-labeled 2-hydroxy-N-[(5-hydroxy-[5-3H]-1,3,3-trimethylcyclohexyl)methyl]-5-methylbenzamide

Douglas D. Dischino, Nicholas A. Meanwell, Hiromi Morimoto, Bradley C. Pearce, Chit Than, Albert F. Torri, Philip G. Williams, Kuo-Long Yu

Journal:

Journal of Labelled Compounds and Radiopharmaceuticals

Year:

1999

File:

PDF, 221 KB

1999

28

Preclinical pharmacokinetics of a novel HIV-1 attachment inhibitor BMS-378806 and prediction of its human pharmacokinetics

Zheng Yang, Lisa Zadjura, Celia D'Arienzo, Anthony Marino, Kenneth Santone, Lewis Klunk, Douglas Greene, Pin-Fang Lin, Richard Colonno, Tao Wang, Nicholas Meanwell, Steven Hansel

Journal:

Biopharmaceutics & Drug Disposition

Year:

2005

Language:

english

File:

PDF, 207 KB

english, 2005

29

ChemInform Abstract: The Discovery of Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Pharmacophore Search and Physiological Evaluation of Flavonoids.

Y. LI, J. E. STARRETT, N. A. MEANWELL, G. JOHNSON, W. E. HARTE, S. I. DWORETZKY, C. G. BOISSARD, V. K. GRIBKOFF

Journal:

Year:

1997

File:

PDF, 28 KB

1997

30

ChemInform Abstract: Discovery of a Novel Class of BK Channel Openers: Enantiospecific Synthesis and BK Channel Opening Activity of 3-(5-Chloro-2- hydroxyphenyl)-1,3-dihydro-3-hydroxy-6-trifluoromethyl-2H-indol-2-one.

P. HEWAWASAM, N. A. MEANWELL, V. K. GRIBKOFF, S. I. DWORETZKY, C. G. BOISSARD

Journal:

Year:

1997

File:

PDF, 32 KB

1997

31

ChemInform Abstract: A Facile Construction of 4-Hydroxymethylbenzisothiazolone-1,1-dioxide.

K.-S. YEUNG, N. A. MEANWELL, Y. LI, Q. GAO

Journal:

Year:

1998

File:

PDF, 31 KB

1998

32

ChemInform Abstract: A Synthesis of 4-Thiomethylbenzisothiazolone-1,1-dioxide Using HDPT.

K.-S. YEUNG, N. A. MEANWELL

Journal:

Year:

1998

File:

PDF, 33 KB

1998

33

ChemInform Abstract: 1,2-Benzisothiazol-3-one 1,1-Dioxide Inhibitors of Human Mast Cell Tryptase.

Keith D. Combrink, H. Belgin Guelgeze, Nicholas A. Meanwell, Bradley C. Pearce, Pi Zulan, Gregory S. Bisacchi, Daniel G. M. Roberts, Paul Stanley, Steven M. Seiler

Journal:

Year:

1999

File:

PDF, 29 KB

1999

34

ChemInform Abstract: Selective Benzoylation of Primary Amines in the Presence of Secondary Amines.

Tao Wang, Zhongxing Zhang, Nicholas A. Meanwell

Journal:

Year:

1999

File:

PDF, 28 KB

1999

35

ChemInform Abstract: Benzoylation of Dianions: Preparation of Monobenzoylated Derivatives of Symmetrical Secondary Diamines.

Tao Wang, Zhongxing Zhang, Nicholas A. Meanwell

Journal:

Year:

2000

File:

PDF, 31 KB

2000

36

ChemInform Abstract: Regioselective Monobenzoylation of Unsymmetrical Piperazines.

Tao Wang, Zhongxing Zhang, Nicholas A. Meanwell

Journal:

Year:

2000

File:

PDF, 29 KB

2000

37

ChemInform Abstract: The Synthesis and Structure—Activity Relationships of 1,3-Diaryl 1,2,4-(4H)-Triazol-5-ones: A New Class of Calcium-Dependent, Large Conductance, Potassium (Maxi-K) Channel Opener Targeted for Urge Urinary Incontinence.

Piyasena Hewawasam, Matthew Erway, George Thalody, Harvey Weiner, Christopher G. Boissard, Valentin K. Gribkoff, Nicholas A. Meanwell, Nicholas Lodge, John E. Starrett Jr.

Journal:

Year:

2002

File:

PDF, 33 KB

2002

38

A Strategy for the Synthesis of Aryl α-Ketoamides Based upon the Acylation of Anions Derived from Cyanomethylamines Followed by Oxidative Cleavage.

Zhong Yang, Zhongxing Zhang, Nicholas A. Meanwell, John F. Kadow, Tao Wang

Journal:

Year:

2002

File:

PDF, 31 KB

2002

39

ChemInform Abstract: The Mono-functionalization of Symmetrical Polyamines

John A. Bender, Nicholas A. Meanwell, Tao Wang

Journal:

Year:

2002

File:

PDF, 25 KB

2002

40

ChemInform Abstract: A General Method for the Preparation of 4- and 6-Azaindoles.

Zhongxing Zhang, Zhong Yang, Nicholas A. Meanwell, John F. Kadow, Tao Wang

Journal:

Year:

2002

File:

PDF, 32 KB

2002

41

An Effective Procedure for the Acylation of Azaindoles at C-3.

Zhongxing Zhang, Zhong Yang, Henry Wong, Juliang Zhu, Nicholas A. Meanwell, John F. Kadow, Tao Wang

Journal:

Year:

2003

File:

PDF, 118 KB

2003

42

Novel Openers of Ca2+-Dependent Large-Conductance Potassium Channels: Symmetrical Pharmacophore and Electrophysiological Evaluation of Bisphenols.

Yi Li, Graham Johnson, Jeffrey L. Romine, Nicholas A. Meanwell, Scott W. Martin, Steven I. Dworetzky, Christopher G. Boissard, Valentin K. Gribkoff, John E. Jr. Starrett

Journal:

Year:

2003

File:

PDF, 70 KB

2003

43

Fundamental Structure—Activity Relationships Associated with a New Structural Class of Respiratory Syncytial Virus Inhibitor.

Kuo-Long Yu, Yi Zhang, Rita L. Civiello, Kathleen F. Kadow, Christopher Cianci, Mark Krystal, Nicholas A. Meanwell

Journal:

Year:

2003

File:

PDF, 76 KB

2003

44

Selective Monoacylation of Symmetrical Diamines via Prior Complexation with Boron.

Zhongxing Zhang, Zhiwei Yin, Nicholas A. Meanwell, John F. Kadow, Tao Wang

Journal:

Year:

2004

File:

PDF, 141 KB

2004

45

Novel 3′-Deoxy Analogues of the anti-HBV Agent Entecavir: Synthesis of Enantiomers from a Single Chiral Epoxide.

Edward Ruediger, Alain Martel, Nicholas Meanwell, Carola Solomon, Brigitte Turmel

Journal:

Year:

2004

File:

PDF, 61 KB

2004

46

Respiratory Syncytial Virus Inhibitors. Part 2. Benzimidazol-2-one Derivatives

Nicholas A. Meanwell, et al. et al.

Journal:

Year:

2004

File:

PDF, 72 KB

2004

47

Dialkylaminoacetonitrile Derivatives as Amide Synthons. A One-Pot Preparation of Heteroaryl Amides via a Strategy of Sequential SNAr Substitution and Oxidation.

Zhongxing Zhang, Zhiwei Yin, John F. Kadow, Nicholas A. Meanwell, Tao Wang

Journal:

Year:

2004

File:

PDF, 108 KB

2004

48

Acetonitrile Derivatives as Carbonyl Synthons. One-Pot Preparation of Diheteroaryl Ketones via a Strategy of Sequential SNAr Substitution and Oxidation.

Zhiwei Yin, Zhongxing Zhang, John F. Kadow, Nicholas A. Meanwell, Tao Wang

Journal:

Year:

2004

File:

PDF, 124 KB

2004

49

Malononitrile as a Carbonyl Synthon: A One-Pot Preparation of Heteroaryl Amide via a SNAr-Oxidation—Displacement Strategy.

Juliang Zhu, Henry Wong, Zhongxing Zhang, Zhiwei Yin, John F. Kadow, Nicholas A. Meanwell, Tao Wang

Journal:

Year:

2004

File:

PDF, 14 KB

2004

50

Azole-N-acetonitriles as Carbonyl Synthons: A One-Pot Preparation of Heteroaryl Amides from Halides.

Zhongxing Zhang, Zhiwei Yin, John F. Kadow, Nicholas A. Meanwell, Tao Wang

Journal:

Year:

2005

File:

PDF, 27 KB

2005